vt.

1. 歼灭，消灭；彻底击溃；毁灭
   An atomic bomb can annihilate a city.

   一枚原子弹能毁灭一个城市。

2. 废止，使无效；视……为无关重要
   annihilate another's ambition

   使他人的野心化作泡影

v.

1. destroy utterly.
   ▸defeat utterly.
2. Physics  convert (matter) into radiant energy, especially by collision of a particle with an antiparticle.