n.[C]

1. 大灾，大祸，大灾难
   The flood in Venice was a major catastrophe.

   威尼斯的洪水是一场大灾难。

2. 大败，惨败
3. 翻天覆地的事件
4. （悲剧或其他文学作品的）结局
   The catastrophe of a tragedy usually brings death or ruin to the leading character.

   悲剧的结局常常是主角的死亡或彻底失败。

n.

1. an event causing great damage or suffering.
2. the denouement of a drama, especially a classical tragedy.