vt.

1. （熟练地）操作，运用
   Do you know how to manipulate a computer?

   你会使用电脑吗？

2. 巧妙地处理；（用权势等）操纵
   A clever politician knows how to manipulate his supporters.

   机敏的政客懂得如何操纵自己的支持者。

3. 操纵（市场、股票的涨落等）
4. 窜改（帐目等），对……做手脚
   He was arrested for trying to manipulate the company's financial records.

   他因企图窜改公司财务记录而被逮捕。

v.

1. handle or control with dexterity.
2. examine or treat (a part of the body) by feeling or moving it with the hand.
3. control or influence cleverly or unscrupulously.
4. alter or present (data) so as to mislead.