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1. 【俚】（问题的）核心；基本的事实；本质
   I like doing business with people who get right to the nitty-gritty.

   我喜欢跟那种直截了当，一针见血的人做生意。

   Our two sides have agreed to cooperate from now on. Let's get down to the nitty-gritties.

   我们双方都已同意以后要合作，现在让我们谈一下重要的细节吧。

n.