n.

1. 悲痛，悲伤[U]
   Mother went mad with grief after the child died.

   孩子死后，母亲因悲痛而发疯了。

2. 悲痛的缘由[C]
   Her heroin-addicted husband is a grief to her.

   她那吸海洛因成瘾的丈夫真让她痛心。

3. 不幸；灾难；失败[U][C]

n.

1. intense sorrow, especially caused by someone's death.
   ▸an instance or cause of intense sorrow.
2. informal trouble or annoyance.